Huntington’s disease may be driven by slowed protein-building machinery in cells
Subramaniam shows that the mutated huntingtin protein slows brain cells’ protein-building machines, called ribosomes.
Posted in
Immunology
Mutated Coronavirus Shows Significant Boost in Infectivity
Mutations to SARS-CoV-2 in mid 2020 made the virus' spike proteins more stable, improving its ability to infect cells.
Treating Cancer Drug Resistance May Come at a Cost to Immune System, Study Suggests
Inhibiting the key gene involved in cancer drug resistance could dull the anti-cancer immune response by inhibiting a type of T lymphocytes, a study from Sundrud lab finds.
Gene Therapy Switch Allows Control of Gene Therapy Doses
JUPITER, FLA – Scientists at UF Scripps Biomedical Research have developed a special molecular switch that could be embedded into gene therapies to allow doctors to control dosing. The feat, reported in the scientific journal Nature Biotechnology, offers gene therapy designers what may be the first viable…
Two-Pronged Antibodies Draw Immune Killers Directly to Cancer Cells
The structure of the ROR1-binding arm of the bi-specific antibody in complex with ROR1 was determined by X-ray crystallography. Our immune system’s arsenal of defenses usually protects us from cancer. But sometimes, cancer cells overwhelm or evade this elaborate defense system. In a study in PNAS, Immunology and Microbiology…
Your Immune System Holds the Line Against Repeat Invaders, Thanks to This Molecule
Researchers found a transcription factor called Runx3 puts dividing T cells on track to becoming memory T cells.
