Neuroscience: News from our Laboratories

Research highlight

Hope for a Rare Genetic Disease

GNAO1-related neurodevelopmental disorders were discovered only in the past decade, and are thought to affect at least hundreds of children around the world.

Martemyanov lab at UF Scripps discovered how a mutated gene leads to symptoms of the GNA01-related neurodevelopmental disorder.

Rhes Protein Key in Spread of Huntington’s…

Nanotube tunnels that act like roadways capable of transporting cargo between cells can transmit a toxic protein linked to Huntington’s disease, a…

Rhes proteins form nanotubes in this neuron. Subramaniam lab.

Search for Safer Pain Relief Advances with New…

“The compound SR-17018 is the first biased agonist of the mu opioid receptor that does not lead to tolerance with chronic use,” says Stahl, a…

Laura Bohn, PhD, Professor and Chair of the Molecular Medicine Department at UF|Scripps with co-author Edward Stahl, Senior Scientist.

Potential Treatment for ALS, Frontotemporal…

Disney designed the ALS compound by applying nearly 15 years of research finding druggable structures on RNA.

Induced neurons derived from ALS patients helped scientists test their compounds.