Michalina Janiszewska

Michalina Janiszewska, Ph.D.

Assistant Professor

Department: SR-MM-JANISZEWSKA LAB
Business Phone: (561) 228-2788
Business Email: mjaniszewska@ufl.edu

About Michalina Janiszewska

Related Links:
Additional Positions:
Instructor of Medicine
2016 – 2018 · Dana-Farber/Harvard Cancer Center
Postdoctoral Research Fellow
2012 – 2016 · Dana-Farber/Harvard Cancer Center
Postdoctoral Research Fellow
2012 – 2012 · CHUV- Lausanne University Hospital

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0002-8592-5146

Publications

2021
Adult precision medicine: learning from the past to enhance the future.
Neuro-oncology advances. 3(1) [DOI] 10.1093/noajnl/vdaa145. [PMID] 33543142.
2021
The impact of tumor epithelial and microenvironmental heterogeneity on treatment responses in HER2-positive breast cancer
JCI Insight. [DOI] 10.1172/jci.insight.147617. [PMID] 33886505.
2020
Cell adhesion in cancer: Beyond the migration of single cells
Journal of Biological Chemistry. 295(8):2495-2505 [DOI] 10.1074/jbc.rev119.007759.
2020
Intratumor Heterogeneity: The Rosetta Stone of Therapy Resistance.
Cancer cell. 37(4):471-484 [DOI] 10.1016/j.ccell.2020.03.007. [PMID] 32289271.
2020
The microcosmos of intratumor heterogeneity: the space-time of cancer evolution
Oncogene. 39(10):2031-2039 [DOI] 10.1038/s41388-019-1127-5. [PMID] 31784650.
2020
YAP-Mediated Recruitment of YY1 and EZH2 Represses Transcription of Key Cell-Cycle Regulators
Cancer Research. 80(12):2512-2522 [DOI] 10.1158/0008-5472.can-19-2415.
2019
Subclonal cooperation drives metastasis by modulating local and systemic immune microenvironments
Nature Cell Biology. 21(7):879-888 [DOI] 10.1038/s41556-019-0346-x. [PMID] 31263265.
2018
A confetti trail of tumour evolution.
Nature cell biology. 20(6):639-641 [DOI] 10.1038/s41556-018-0110-7. [PMID] 29802407.
2018
TRPS1 Is a Lineage-Specific Transcriptional Dependency in Breast Cancer.
Cell reports. 25(5):1255-1267.e5 [DOI] 10.1016/j.celrep.2018.10.023. [PMID] 30380416.
2017
Classifying the evolutionary and ecological features of neoplasms.
Nature reviews. Cancer. 17(10):605-619 [DOI] 10.1038/nrc.2017.69. [PMID] 28912577.
2016
IMPs: an RNA-binding protein family that provides a link between stem cell maintenance in normal development and cancer.
Genes & development. 30(22):2459-2474 [PMID] 27940961.
2016
Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer.
Nature. 529(7586):413-417 [DOI] 10.1038/nature16508. [PMID] 26735014.
2016
Spatial Proximity to Fibroblasts Impacts Molecular Features and Therapeutic Sensitivity of Breast Cancer Cells Influencing Clinical Outcomes.
Cancer research. 76(22):6495-6506 [DOI] 10.1158/0008-5472.CAN-16-1457. [PMID] 27671678.
2016
The RNA Binding Protein IMP2 Preserves Glioblastoma Stem Cells by Preventing let-7 Target Gene Silencing.
Cell reports. 15(8):1634-47 [DOI] 10.1016/j.celrep.2016.04.086. [PMID] 27184842.
2015
Clonal evolution in cancer: a tale of twisted twines.
Cell stem cell. 16(1):11-2 [DOI] 10.1016/j.stem.2014.12.011. [PMID] 25575078.
2015
In situ single-cell analysis identifies heterogeneity for PIK3CA mutation and HER2 amplification in HER2-positive breast cancer.
Nature genetics. 47(10):1212-9 [DOI] 10.1038/ng.3391. [PMID] 26301495.
2014
Tumor heterogeneity: the Lernaean hydra of oncology?
Oncology (Williston Park, N.Y.). 28(9):781-2, 784 [PMID] 25224477.
2012
Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells.
Genes & development. 26(17):1926-44 [DOI] 10.1101/gad.188292.112. [PMID] 22899010.
2011
Let-7a is a direct EWS-FLI-1 target implicated in Ewing’s sarcoma development.
PloS one. 6(8) [DOI] 10.1371/journal.pone.0023592. [PMID] 21853155.
2010
EWS-FLI-1 modulates miRNA145 and SOX2 expression to initiate mesenchymal stem cell reprogramming toward Ewing sarcoma cancer stem cells.
Genes & development. 24(9):916-32 [DOI] 10.1101/gad.1899710. [PMID] 20382729.
2010
Transportin regulates nuclear import of CD44.
The Journal of biological chemistry. 285(40):30548-57 [DOI] 10.1074/jbc.M109.075838. [PMID] 20663864.
2009
Epigenetic features of human mesenchymal stem cells determine their permissiveness for induction of relevant transcriptional changes by SYT-SSX1.
PloS one. 4(11) [DOI] 10.1371/journal.pone.0007904. [PMID] 19936258.
2009
EZH2 is essential for glioblastoma cancer stem cell maintenance.
Cancer research. 69(24):9211-8 [DOI] 10.1158/0008-5472.CAN-09-1622. [PMID] 19934320.
Collateral lethality between HDAC1 and HDAC2 exploits cancer-specific NuRD complex vulnerabilities
. [DOI] 10.1101/2022.05.30.493851.
Single-cell genetic heterogeneity linked to immune infiltration in glioblastoma
. [DOI] 10.1101/2021.09.20.461080.

Education

Ph.D. in Life Sciences
2012 · University of Lausanne
Master's of Science in Medical Biotechnology
2007 · University of Wroclaw
Bachelor's of Science in Biotechnology
2005 · University of Wroclaw

Contact Details

Phones:
Business:
(561) 228-2788
Emails:
Addresses:
Business Mailing:
Location C251
130 SCRIPPS WAY BLDG 2C1
JUPITER FL 33458