The natural products collection at Scripps Florida contains hundreds of thousands of organisms available for study. Advance provides new tools for synthetic chemists and biologists looking to probe and modify sulfur-based biochemistry JUPITER, FL—A group of highly reactive compounds called persulfides have provoked great curiosity among biochemists,…
Alicia Angelbello, Ph.D., a student of the Skaggs Graduate School, studied with UF Scripps Chemistry Department Chair Matthew Disney, Ph.D. She has been awarded the American Chemical Society’s Nobel Signature Award. UF Scripps Chemist Matthew Disney and Skaggs Graduate School student Alicia Angelbello devised a way to potentially treat a…
Kendall Nettles, PhD, (center) meets with two students in his lab, Jacqline Njeri (left) and Charles Min (right). Nettles and colleagues designed drug-like molecules that appear to fight estrogen-sensitive breast cancer in two ways, in cell studies. Njeri and Min are co-authors on the paper, published August 27, 2021, in…
Like a carpenter switching drill bits depending on the job at hand, scientists at Scripps Research in Florida have changed an investigational medicine’s activity by swapping in different molecular tools, in the process, showing a potential new way to address multiple incurable diseases.
Mutations to Dyrk1a gene lead to brain undergrowth with features of autism and intellectual disability. An existing drug rescues the condition in newborn mice, Scripps Florida scientists find.
Study reveals how T cells in the small intestine respond to bile acids, offering localized treatment direction for a cause of chronic illness.
GNAO1 neurodevelopmental disorders were discovered only in the past decade. Martemyanov's team at UF Scripps discovered the mechanism underlying the disorder's devastating symptoms.
A study from Martemyanov lab solves the mystery of how cones form their distinctive brain connections, giving humans and other animals their sophisticated and powerful vision sense.
The three enzymes used, to construct the terpines were identified only last year, from the microbial strain collection at UF Scripps' Natural Products Discovery Center.
Inhibiting the key gene involved in cancer drug resistance could dull the anti-cancer immune response by inhibiting a type of T lymphocytes, a study from Sundrud lab finds.