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Gene Therapy Switch Allows Control of Gene Therapy Doses

JUPITER, FLA – Scientists at UF Scripps Biomedical Research have developed a special molecular switch that could be embedded into gene therapies to allow doctors to control dosing. The feat, reported in the scientific journal Nature Biotechnology, offers gene therapy designers what may be the first viable…

PTSD Study Identifies Potential Target for Memory Disruption

Professor Courtney Miller, PhD, of the departments of Neuroscience and Molecular Medicine. JUPITER, FL — Fight or flight, panic, trembling: Our brains are wired to ensure we respond instantly to fear. While that fear response may save our lives in the dangerous moment, at times people stay on high…

Two-Pronged Antibodies Draw Immune Killers Directly to Cancer Cells

The structure of the ROR1-binding arm of the bi-specific antibody in complex with ROR1 was determined by X-ray crystallography. Our immune system’s arsenal of defenses usually protects us from cancer. But sometimes, cancer cells overwhelm or evade this elaborate defense system. In a study in PNAS, Immunology and Microbiology…